| 產品名稱 |
Squirrel fibroma virus |
| 商品貨號 |
B204846 |
| Classification |
Poxviridae, Leporipoxvirus, Myxoma virus |
| Deposited As |
Fibroma virus |
| Agent |
Squirrel fibroma virus |
| Strain |
Kilham |
| Common Name |
Squirrel fibroma virus |
| Applications |
The virus will produce lesions in the skin of domestic rabbits, but efforts to pass it serially in rabbits have not been successful. |
| Biosafety Level |
2
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Isolation |
Naturally occurring fibroma of gray squirrels (Sciurus carolinensis), Maryland, 1952 |
| Product Format |
frozen |
| Storage Conditions |
-70°C |
| Comments |
The virus will produce lesions in the skin of domestic rabbits, but efforts to pass it serially in rabbits have not been successful. Tumors apperar in 3 days and commence to regress in 6 days. Young woodchucks are usually susceptible (i.d.), and tumors may persist for 6 weeks. Tumors develop in young and in adult infected squirrels in 1 to 2 weeks. |
| Effect on Host |
cytopathic effects in primary rabbit kidney cells (The virus causes eventual degeneration of cell monolayer, focal piling of cells occurs during replicatication. Replication of virus may occur without cytopathetic effects in other types of tissue culture cells.) |
| Recommended Host |
rabbit kidney cells; monkey kidney cells; monkey rabbit kidney cells; squirrel kidney cells; young woodchuck (Mamorata monax) |
| Growth Conditions |
Incubation: 3-7 days |
| Name of Depositor |
L Kilham |
| Special Collection |
ATCC |
| Source |
Naturally occurring fibroma of gray squirrels (Sciurus carolinensis), Maryland, 1952 |
| Year of Origin |
1952 |
| References |
Kilham L, et al. Naturally occurring fibromas of grey squirrels related to Shope's rabbit fibroma. Proc. Soc. Exp. Biol. Med. 82: 298-301, 1953. PubMed: 13037878
The virus causes eventual degeneration of cell monolayer, focal piling of cells occurs during replicatication. Replication of virus may occur without cytopathetic effects in other types of tissue culture cells.
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